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ความก้าวหน้าทางวิทยาการ
สาเหตุของโรคและปัญหา
ทางด้านสุขภาพชนิดต่างๆ
Innovative Clinical
News. Disease and
Condition
Eating Disorders
โรคความผิดปกติของการกิน
- Anorexia Nervosa
- Bulimia Nervosa
- Compulsive
Overeating


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Prevalence of Eating Disorders:
Each year, millions of people in the United States succumb to potentially
life-threatening eating disorders. Estimates of people afflicted with Anorexia
Nervosa and Bulimia Nervosa in the United States range from 2% to 6%. This
implies that between 5 and 16 million people suffer from these disorders.
Approximately 90% of those afflicted with these disorders are women. The
potentially fatal disease, Anorexia Nervosa, occurs within the population at
approximately .5% to 2%. Estimates for the occurrence of Bulimia Nervosa range
between 1% to 4% of the population. Although eating disorders can affect people of
all ages, 86% of individuals afflicted with these disorders report the onset before the
age of 20. The occurrence of eating disorders among college age women can
almost be considered epidemic. Between 19% and 30% of this age group display
bulimic behavior. The current trend is that eating disorders are affecting younger and
younger individuals. It is estimated that currently 11% of high school students may
have a diagnosable eating disorder. Athletes and dancers may face a greater risk
for developing an eating disorder. In ballet, for example, success may depend on
the attainment of a wiry and extremely thin body type. For athletes, particularly
women in “appearance sports” which include gymnastics and figure skating,
appearance also seems to play a key role in success. Of females who participate
in these types of athletic activities, as well as track and cross-country, 62% have
been reported to have eating disorders.
Course and Outcome of Eating Disorders:
The onset for Anorexia Nervosa and Bulimia Nervosa is usually during late
adolescence or early adulthood. The illnesses usually begin following a stressful
life event. Many eating disordered individuals feel out of control with their life and
through the practice of the eating disorder get a false sense of control. They often
went through a period of being overweight and being teased or felt left out because
of their weight. Their first attempts at weight loss were often met with success and
positive comments from their family and peers. Of individuals with eating disorders,
77% usually practice their eating disorders between 1 and 15 years. Eating
disorders are among the deadliest mental disorders with up to 10% succumbing to
death as a result of starvation, cardiac arrest, or suicide. Eating disorders are most
successfully treated with early diagnosis. For anorexics that receive treatment, 40%
recover completely, 40% make only partial recovery, and 20% have chronic
problems. For bulimics, 50% recover completely, 35% have some bulimic episodes,
and 15% still have chronic problems with their bulimia.
Medical Complications of Eating Disorders
ความผิดปกติร่างกายทางการแพทย์อันมีผลจากโรคความผิดปกติการกิน
The following is a list of possible medical complications that accompany Eating
Disorders. If left untreated the physical complications from practicing an eating
disorder can become life threatening.
CARDIOVASCULAR -
ความผิดปกติระบบการไหลเวียนโลหิต
Slow pulse
Low blood pressure
Electrocardiogram abnormalities
Hypovolemia
Myocardiopathy and CHF (especially with use of ipecac)
CHEMISTRIES -
ความผิดปกติของสารเคมีในร่างกาย
Uric acid elevated
Cholesterol is abnormal (elevated or depressed)
Carotene is elevated
Deficiencies of trace minerals
Low blood glucose
Hypochloremic metabolic alkalosis
DENTAL AND MOUTH -
ความผิดปกติของสุขอนามัยในช่องปากและฟัน
Increased dental caries
Highly sensitive teeth from gingival deterioration
Pyorrhea
Lacerations and contusions of the oral cavity from use of objects to induce emesis
Tooth Loss
Erosion of enamel
Altered bite
Bleeding gums
Oral sensitivity
DERMATOLOGIC -
ความผิดปกติของผิวหนัง
Dry skin
Loss of subcutaneous tissues and fat in general
Scars (such as on knuckles due to inducing emesis)
Fine lanugo hair
Acrocyanosis
EFFECTS ON BRAIN AND CNS -
ผลต่อระบบประสาทส่วนกลางและสมอง
Lack of REM sleep
Affected hypothalamus (lower body temperature, loss of shivering response, cold intolerance, and malfunction of entire temperature regulating system) due to chronic malnutrition
EEG abnormalities
ENDOCRINE -
ผลต่อระบบฮอร์โมนและต่อมไร้ท่อ
T-3 deficiency (leading to bradycardia, sluggish reflexes, dry skin, cold intolerance, hypercarotenemia, and various abnormalities of the hair)
Abnormal calcium levels and symptoms
Hypogonadism
Partial diabetes insipidus condition and the inability to concentrate urine normally
Addisons disease or hyperaldosteronism
FLUID AND ELECTROLYTE ABNORMALITIES
ความผิดปกติสมดุลของอีเลคโทรไลท์
และระดับน้ำในร่างกาย
Effects of resultant metabolic alkalosis, potassium and chloride deficiencies
Electrolyte Imbalance
Skeletal muscle weakness
Diminished reflexes
Abnormal gastrointestinal motility
Cramps
Paresthesia
Polyuria and oliguria
Nocturia
CNS abnormalities
Constipation
Cardial effects (conduction abnormalities, irregular rhythms and sudden death)
Impaired kidney function
Emotional lability and lassitude
Potassium increase due to diuretic abuse causing cardiac abnormalities
Depletion of sodium (hyponatremia)
Dehydration
Hyponatremia
Edema
GASTROINTESTINAL -
ความผิดปกติของระบบทางเดินอาหาร
Abdominal pain, bloating, and fullness
Esophageal perforations and lacerations (Mallory-Weiss Syndrome)
Irritable bowel syndrome
Ulceration of the bowel
Malabsorption of nutrients leading to hypoproteinemia, hypoalbuminemia and calcium deficiency
Fatty infiltration of the liver
Pancreatitis
Exacerbation of hemorrhoids
Esophagitis
Melanosis coli
Gastritis
Gastric ulceration
Intestinal injury
GYNECOLOGIC -
ความผิดปกติของระบบเจริญพันธุ์
Menstrual irregularity
Amenorrhea
Infertility
Atrophic vaginitis and loss of sexual appetite
Breast atrophy
HEMATOLOGIC ABNORMALITIES -
ความผิดปกติของเม็ดโลหิต
Anemia
Leukopernia
Thrombocytopenia
Bone marrow may be deficient or hypocellular
OPHTHALMOLOGIC -
ความผิดปกติของระบบการมองเห็น
Transient blurred vision
Dark circles, puffiness under the eyes
ORTHOPEDIC AND MUSCULOSKELETAL
ความผิดปกติของระบบโครงสร้างและกระดูก
Osteoporosis
Loss of muscle mass leading to muscular weakness
PULMONARY -
ความผิดปกติของระบบทางเดินหายใจ
Aspiration pneumonia
RENAL -
ความผิดปกติของระบบขับถ่ายปัสสาวะ
Prerenal and renal azotemia due to diminished renal pertusion and chronic dehydration
Tubular and collecting system abnormalities due to electrolyte abnormality
Predisposition to renal stones
Kidney failure
MISCELLANEOUS -
ความผิดปกติอื่นๆ
เช่นระบบภูมิคุ้มกัน
Bacterial and fungal infections
Bilateral parotid gland swelling

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