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ลักษณะโครงสร้างของเล็บ
Nail Anatomy
ความผิดปกติของเล็บจาก
การแพ้/ สัมผัส
กับสารเคมี
Aging
ความผิดปกติของเล็บจาก
เชื้อรา
Fungi
ความผิดปกติของเล็บจาก
ยิสต์และแบคทีเรีย
Bacteria & Yeast
ความผิดปกติของเล็บจาก
การถูกกระแทก
Trauma
ความผิดปกติของเล็บจาก
โรคสะเก็ดเงิน
Psoriasis
ความผิดปกติของเล็บจาก
เอคซีม่า
Eczema
ความผิดปกติของเล็บจาก
เชื้อไลเคนส์
Lichen planus
ความผิดปกติของเล็บจาก
โรคอื่นๆที่มีผลต่อเล็บ
Internal Disease
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Eczema
Nail rippling and
nail plate distortion occurs with chronic paronychia or chronic eczematous
inflammation of the proximaland and lateral nailfolds. The ripples of
chronic inflammation appear as rounded waves, in contrast to the closely
spaced, sharp grooves produced by continual manipulation. Pitting can also
be created by chronic inflammation of the nail folds


เชื้อไลเคนส์
Lichen planus
Approximately 25% of patients with nail lichen planus (LP) have LP in
other sites before or after the onset of nail lesions. Nail LP usually
appears during the fifth or sixth decade of life. The matrix, nail bed,
and nailfolds may be involved in producing a variety of changes, few of
which are characteristic.
Minimal
inflammation of the matrix induces longitudinal grooving and ridging,
which are the most common findings of LP of the nail. The development of
severe and early destruction of the nail matrix with scarring
characterizes a small subset of patients with nail LP.
A pterygium, caused
by adhesion of a depressed proximal nailfold to the scarred matrix, may
occur after intense matrix inflammation. The nail plate distal to this
focus is either absent or thinned out. In most cases, nail LP is
self-limiting or promptly regresses with treatment. Permanent damage to
the nail is uncommon, even in patients with diffuse involvement of the
matrix.
Treatment
Matrix lesions may
respond to intralesional triamcinolone acetonide (2.5 to 5 mg/ml)
delivered with a 30-gauge needle every 3 or 4 weeks. Severe cases respond
to prednisone (20 to 40 mg/day). This may require a long course of
treatment in which the possible risks may outnumber the advantages.

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ความผิดปกติของเล็บจากโรคอื่นๆที่มีผลต่อเล็บ
Internal Disease
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There are many internal
diseases that can alter the appearance of the nail plate . Three of
the most common diseases can be seen by pushing the buttons on the
left.
Check this sight again for a
table of all internal diseases affecting the nail plate and tables
showing diseases that cause color changes of the nails.
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Finger
clubbing
Finger clubbing
(Hippocratic nails) is a distinct feature associated with a number of
diseases, but it may occur as a normal variant. The distal phalanges of
the fingers and toes are enlarged to a rounded, bulbous shape. The nail
enlarges and becomes curved, hard, and thickened. The angle made by the
proximal nailfold and nail plate (Lovibondís angle) increases and
approaches or exceeds 180 degrees. The proximal nailfold feels as though
it is floating on the underlying tissue. Clubbing is associated with a
variety of lung diseases, cardiovascular disease, cirrhosis, colitis,
and thyroid disease. The changes are permanent.
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Beaus lines
Beaus lines
are transverse depressions of all of the nails that appear at the base
of the lunula weeks after a stressful event has temporarily interrupted
nail formation.The lines progress distally with normal nail growth and
eventually disappear at the free edge. They develop in response to many
diseases, such as syphilis, uncontrolled diabetes mellitus, myocarditis,
peripheral vascular disease, and zinc deficiency, and to illness
accompanied by high fevers, such as scarlet fever, measles, mumps, and
pneumonia
Alopecia areata
Many patients with alopecia areata have shallow pitting or surface
stippling in a uniform or grid like pattern . The pits are are of uniform
depth, psoriatic pits are usually deeper and are haphazardly distributed
on the nail plate surface

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